Warning: charset "UTF-8" not supported, using "ISO8859-1". aborting
This problem occurs if your locale is set to one that uses UTF-8, which many distributions are now defaulting to. On other distributions (such as Debian and Slackware), AcrobatReader prints out the warning but doesn't abort. The locale(1) command will tell you what your locate is set to.
The workaround is to edit $PREFIX/Acrobat5/bin/acroread and add the following lines near the top
LANG=C export LANG
See the UnicodeNotes page if you have no idea what "UTF-8" or "ISO-8859-1" means. :-)
Adobe Reader 6.0 (only available on MicrosoftWindows) launches slowly because it loads a lot of usually superfluous plugins. Remove all files except for EWH32.api, printme.api, and search.api from the C:\Program Files\Adobe\Acrobat 6.0\Reader\plug_ins directory (change this depending on where Reader is installed) and it will launch much faster.
Similar speedups can be achieved with other versions, including the older ones for Linux, where the directory is $PREFIX/Acrobat5/Reader/intellinux/plug_ins/.
Go to File → Print as usual. In the Page Scaling dropdown in the Page Handling section, pick Multiple Pages Per Sheet. This will reveal other options to adjust how many pages will be printed on a single sheet. Very handy for bulk print jobs.