Every so often an IPv6 router is supposed to send out Router Advertisements saying what IPv6 range(s) should be used on this subnet allowing a host to autoconfigure itself by appending it's MAC address to the IPv6 address and using that. So it's kinda like a built in DHCP.
Some gotcha's
Other than that, it means that desktop machines and the like just plugin and work, no configuration necessary. Very cool.
Here's a page about how to configure RouterAdvertisements on debian, (although it's not very Debian specific): http://people.debian.org/csmall/ipv6/setup.html
Don't worry about your IPv6 boxes having several IP addresses per Interface. IPv6 enabled box collect them like stamps.
One page links to RouterAdvertisements: